A brain-wave equation incorporating axo-dendritic connectivity


Ross, J, Margetts, M., Bojak, I., Nicks, R., Avitabile, D., and Coombes, S.


We introduce an integral model of a two-dimensional neural field that includes a third dimension representing space along a dendritic tree that can incorporate realistic patterns of axodendritic connectivity. For natural choices of this connectivity we show how to construct an equivalent brain-wave partial differential equation that allows for efficient numerical simulation of the model. This is used to highlight the effects that passive dendritic properties can have on the speed and shape of large scale traveling cortical waves.



  title = {Brain-wave equation incorporating axodendritic connectivity},
  author = {Ross, James and Margetts, Michelle and Bojak, Ingo and Nicks, Rachel and Avitabile, Daniele and Coombes, Stephen},
  journal = {Phys. Rev. E},
  volume = {101},
  issue = {2},
  pages = {022411},
  numpages = {9},
  year = {2020},
  month = {Feb},
  publisher = {American Physical Society},
  doi = {10.1103/PhysRevE.101.022411},
  url = {https://link.aps.org/doi/10.1103/PhysRevE.101.022411}